{"id":14874,"date":"2024-03-27T16:25:05","date_gmt":"2024-03-27T15:25:05","guid":{"rendered":"https:\/\/www.sling.si\/?post_type=wpdmpro&#038;p=14874"},"modified":"2025-07-16T13:50:55","modified_gmt":"2025-07-16T11:50:55","slug":"drug-discovery-with-a-supercomputer","status":"publish","type":"wpdmpro","link":"https:\/\/www.sling.si\/en\/download\/drug-discovery-with-a-supercomputer\/","title":{"rendered":"Drug discovery with a supercomputer"},"content":{"rendered":"<p>In the development of new medicinal compounds, research laboratories employ robotic equipment for high-throughput screening (HTS), which enables automated experimental in vitro biological evaluation of various compounds with a capacity of several hundred thousand compounds [1]. With the rapid advancement of computer science, this relatively expensive and complex process is complemented and being replaced by computational tools for molecular modelling.\u00a0 Similar to experiments conducted <em>in vivo<\/em> or <em>in vitro<\/em>, we can also refer to experiments conducted <em>in silico<\/em>, which\u00a0literally\u00a0means in silicon, essentially referring to computer simulation.<\/p>\n<p>Download the entire article:<\/p>\n<p><a href=\"https:\/\/www.sling.si?wpdmdl=14874&amp;ind=1713965971294\"><img loading=\"lazy\" decoding=\"async\" class=\"fy-content-image fy-lazy js-lazy alignnone\" src=\"data:image\/svg+xml,%3Csvg%20width%3D%2280%22%20height%3D%2280%22%20xmlns%3D%22http:\/\/www.w3.org\/2000\/svg%22%20viewBox%3D%220%200%2080%2080%22%3E%3C\/svg%3E\" alt=\"Download the entire article\" width=\"80\" height=\"80\" data-src=\"https:\/\/www.sling.si\/wp-content\/plugins\/download-manager\/assets\/file-type-icons\/resume-download.png\"><div class=\"fy-image-loading fy-image-loading--spinner\" aria-hidden=\"true\"><\/div><\/a><\/p>\n<p>Authors: Davor Sluga, Ratko Pilipovi\u0107, Nejc Ilc; University of Ljubljana<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the development of new medicinal compounds, research laboratories employ robotic equipment for high-throughput screening (HTS), which enables automated experimental in vitro biological evaluation of various compounds with a capacity &#8230;<\/p>\n","protected":false},"author":13,"featured_media":14550,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"__wpdm_changelog":[]},"wpdmcategory":[547],"wpdmtag":[544,485,546,468,543,488,487,545,483,657,486],"class_list":["post-14874","wpdmpro","type-wpdmpro","status-publish","has-post-thumbnail","hentry","wpdmcategory-educational-article","wpdmtag-drug-discovery","wpdmtag-fri-ul","wpdmtag-healthcare","wpdmtag-hpc","wpdmtag-hpc-in-medicine","wpdmtag-hpc-v-medicini","wpdmtag-medicina","wpdmtag-medicine","wpdmtag-superracunalnistvo","wpdmtag-ul","wpdmtag-zdravila"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/wpdmpro\/14874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/wpdmpro"}],"about":[{"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/types\/wpdmpro"}],"author":[{"embeddable":true,"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/comments?post=14874"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/media\/14550"}],"wp:attachment":[{"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/media?parent=14874"}],"wp:term":[{"taxonomy":"wpdmcategory","embeddable":true,"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/wpdmcategory?post=14874"},{"taxonomy":"wpdmtag","embeddable":true,"href":"https:\/\/www.sling.si\/en\/wp-json\/wp\/v2\/wpdmtag?post=14874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}